I was using Acuvue Oasys for about 2 years up until Feb of 2009 when I started having problems. My eyes became severely red, actually that is an understatement. They were blood red. I had to completely stop wearing them. I visited my ophthamologist and received steroid treatments to clear that up. He never did say if he thought there was something wrong with the contacts themselves. He thinks I became severely allergice to the protein buildup on the lense themselves.(That's funny because I was routinesly using a protein remover!)I am now wearing Acuvue 1 day Moist and they are working fine. I am also on antihistamine treatments twice a day.