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Biofinity Problems?

This is a discussion on Biofinity Problems? within the Biofinity forums; Have you ever had any issues with sore eyes or itching or anything like that ...


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  #1 (permalink)  
Old 07-29-2008, 04:01 PM
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Default Biofinity Problems?

Have you ever had any issues with sore eyes or itching or anything like that and it turned out to be because you had the wrong cleaning solution?
Would you mind telling us about it?
Thanks.
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  #2 (permalink)  
Old 08-07-2008, 11:32 AM
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Default

Aviod solutions containing "Biguanides" as the disinfecting agent. This compound tends to bind proteins in your tears to high silicon/water content contact lenses
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  #3 (permalink)  
Old 08-08-2008, 09:41 AM
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Default Biofinity Problems?

Quote:
Originally Posted by VirginiaEyeDr View Post
Aviod solutions containing "Biguanides" as the disinfecting agent. This compound tends to bind proteins in your tears to high silicon/water content Contact lenses
Thank you for your replay, VirginiaEyeDr. It's great to have a real doctor on board.

So what are the symptoms of protein buildup on your contact lenses? Burning and itching like I mentioned before?
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  #4 (permalink)  
Old 01-21-2010, 04:50 PM
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Default is there a reference for this?

Quote:
Originally Posted by VirginiaEyeDr View Post
Aviod solutions containing "Biguanides" as the disinfecting agent. This compound tends to bind proteins in your tears to high silicon/water content Contact lenses
very interesting, reference?
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  #5 (permalink)  
Old 01-22-2010, 10:12 AM
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Default Interesting

Quote:
Originally Posted by rfriel View Post
very interesting, reference?
It is? What do you mean? Something about "biguanides"?
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  #6 (permalink)  
Old 01-22-2010, 10:40 AM
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Default Do not

Quote:
Originally Posted by rfriel View Post
very interesting, reference?
biguanides dont bind protein to tears, where did you get that misinformation?

Last edited by rfriel; 01-22-2010 at 10:40 AM.. Reason: spelling
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  #7 (permalink)  
Old 01-22-2010, 11:36 AM
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Default

Quote:
Originally Posted by rfriel View Post
biguanides dont bind protein to tears, where did you get that misinformation?
Read the VirginiaEye Dr post again!

It said: Biguanides tend to bind the protein IN YOUR tears to high Silicone/Water Content lenses, not bind protein to the tears.

(I don't know if this is true, just correcting your reference to the earlier post).

knotlob
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  #8 (permalink)  
Old 01-22-2010, 11:39 AM
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Default OK, where's the FRICKEN REFERENCE!!!!

Quote:
Originally Posted by Knotlob View Post
Read the VirginiaEye Dr post again!

It said: Biguanides tend to bind the protein IN YOUR tears to high Silicone/Water Content lenses, not bind protein to the tears.

(I don't know if this is true, just correcting your reference to the earlier post).

knotlob
F**** REFERENCE!!! or just cause I said so?? yeah, whatever.....
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  #9 (permalink)  
Old 01-22-2010, 12:13 PM
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Default Calm Down

Quote:
Originally Posted by rfriel View Post
F**** REFERENCE!!! or just cause I said so?? yeah, whatever.....
Hey, be nice to Knotlob. He knows what he's talking about. What's with you anyway? Are you here just to make trouble? Can't we all just get along?
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  #10 (permalink)  
Old 01-22-2010, 12:15 PM
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Default Do You Mean . . .

Quote:
Originally Posted by rfriel View Post
very interesting, reference?
Oh, do you mean "That's very interesting. Can you tell me where you got that information?"?
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  #11 (permalink)  
Old 01-22-2010, 12:22 PM
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Default got it from virginiaeyedr

Quote:
Originally Posted by Banditcat View Post
Oh, do you mean "That's very interesting. Can you tell me where you got that information?"?
so it has to be true, the doc told me so...... the doc said so, that's the golden word to be believed above all else, should we bow down to the doc??

Last edited by rfriel; 01-22-2010 at 12:24 PM.. Reason: fdsfads
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  #12 (permalink)  
Old 01-22-2010, 05:35 PM
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Default

Quote:
Originally Posted by rfriel View Post
so it has to be true, the doc told me so...... the doc said so, that's the golden word to be believed above all else, should we bow down to the doc??
It's perfectly in order to ask for a reference if one is available (but politely please). I think we would all be interested in reading more info on how the Biguanides are acting in binding protein to Silicone Hydrogel lenses if VirginiaEyeDr can point us in the right direction.

I had not heard that before, but I am told that for RGP lenses (in my case Menicon Z Alpha) I must intensively clean the lenses weekly. The routine sterilising compound recommended for day to day use, uses Biguanide as the active ingredient, though I think I would prefer the more thorough two step peroxide for 100% disinfection. But I cannot switch until I have discussed that with Menicon.

Of course RGP lenses use an entirely different silicone polymer to that used in the soft lenses.

knotlob
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Old 03-23-2010, 04:24 PM
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Default Don't Be Like That

Quote:
Originally Posted by rfriel View Post
so it has to be true, the doc told me so...... the doc said so, that's the golden word to be believed above all else, should we bow down to the doc??
Why are you so upset, rfriel? Nobody's trying to pick on you. Why do you have to be like that?
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Old 03-23-2010, 04:47 PM
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Default i'm not upset,

Quote:
Originally Posted by Banditcat View Post
Why are you so upset, rfriel? Nobody's trying to pick on you. Why do you have to be like that?
i am telling you what action i do, what makes you think or believe i am upset?? it's an action not an emotion........
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  #15 (permalink)  
Old 04-07-2010, 10:30 AM
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Default

Quote:
Originally Posted by rfriel View Post
i am telling you what action i do, what makes you think or believe i am upset?? it's an action not an emotion........
"F**** REFERENCE!!! or just cause I said so?? yeah, whatever....."

If that's not "upset" then I'd hate to see how you react when you really do get upset . . .

Now, what is this about a reference again?
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  #16 (permalink)  
Old 04-26-2010, 02:53 PM
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Default What Are They There For?

Quote:
Originally Posted by VirginiaEyeDr View Post
Aviod solutions containing "Biguanides" as the disinfecting agent. This compound tends to bind proteins in your tears to high silicon/water content contact lenses
If these Biguanides make proteins stick to your contact lenses, why do some contact lens solutions contain them?
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  #17 (permalink)  
Old 05-03-2010, 04:45 PM
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Default In Case Your Eyes Are Diabetic?

Quote:
Originally Posted by yournamehere View Post
If these Biguanides make proteins stick to your contact lenses, why do some contact lens solutions contain them?
What are these "Biguanides" anyway? I tried looking them up in Wikipedia, but all I read was stuff like "a molecule, or to a class of drugs based upon this molecule. Biguanides can function as oral antihyperglycemic drugs used for diabetes mellitus or prediabetes treatment. They are also used as antimalarial drugs."

What on Earth does this have to do with contact lenses?
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  #18 (permalink)  
Old 05-03-2010, 05:17 PM
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Default

Quote:
Originally Posted by Banditcat View Post
What are these "Biguanides" anyway? I tried looking them up in Wikipedia, but all I read was stuff like "a molecule, or to a class of drugs based upon this molecule. Biguanides can function as oral antihyperglycemic drugs used for diabetes mellitus or prediabetes treatment. They are also used as antimalarial drugs."

What on Earth does this have to do with contact lenses?
The 'biguanide' I refer to is polyaminopropyl biguanide (DYMED) and is used in Multi Purpose Disinfecting & Cleaning Solutions. I prefer to use a two part hydrogen peroxide cleaning system, which is more thorough than the multipurpose cleaning & disinfecting solutions, but needs time to neutralise the peroxide before insertion into the eye.

VirginiaEyeDoctor believes the Biguanide based system binds to high water content and/or silicone hydrogel lens structures (which would make deposit build up worse).

knotlob
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  #19 (permalink)  
Old 05-04-2010, 09:57 AM
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Default Biofinity Biguanide Buildup

Quote:
Originally Posted by Knotlob View Post
VirginiaEyeDoctor believes the Biguanide based system binds to high water content and/or silicone hydrogel lens structures (which would make deposit build up worse).

knotlob
You sound as though you don't necessarily agree. Biguanides or not, do you think that silicone hydrogel contact lenses have a particular problem with build-up?
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  #20 (permalink)  
Old 05-04-2010, 10:10 AM
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Default

Quote:
Originally Posted by KITT View Post
You sound as though you don't necessarily agree. Biguanides or not, do you think that silicone hydrogel contact lenses have a particular problem with build-up?

I have to take VirginaEyeDoctor's word for the time being. However, I accept his/her statement as I think I have seen words to that effect elsewhere, but would prefer to see the academic backup.

I don't really like to use a Biguanide type cleaning/disinfection system as it just isn't as effective at destroying more persistent microbiological agents. I use a two part peroxide for that reason.

I also find that the biguanide system I was recommended to use for RGP lenses seems to create grit from dried solution products, which is very uncomfortable in my eyes.

knotlob
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  #21 (permalink)  
Old 05-04-2010, 10:20 AM
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Default That Was Fast

Quote:
Originally Posted by Knotlob View Post
I have to take VirginaEyeDoctor's word for the time being. However, I accept his/her statement as I think I have seen words to that effect elsewhere, but would prefer to see the academic backup.

I don't really like to use a Biguanide type cleaning/disinfection system as it just isn't as effective at destroying more persistent microbiological agents. I use a two part peroxide for that reason.

I also find that the biguanide system I was recommended to use for RGP lenses seems to create grit from dried solution products, which is very uncomfortable in my eyes.

knotlob

knotlob
Thanks for answering so quickly, Knotlob. It looks like I caught you while you were on line.
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  #22 (permalink)  
Old 07-28-2010, 04:57 PM
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Default Protein Binder

Quote:
Originally Posted by VirginiaEyeDr View Post
Aviod solutions containing "Biguanides" as the disinfecting agent. This compound tends to bind proteins in your tears to high silicon/water content Contact lenses
So that means, in layman's terms, that your contacts quickly become gunky?
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  #23 (permalink)  
Old 07-29-2010, 09:44 AM
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Default

Quote:
Originally Posted by Knotlob View Post
I have to take VirginaEyeDoctor's word for the time being. However, I accept his/her statement as I think I have seen words to that effect elsewhere, but would prefer to see the academic backup.

I don't really like to use a Biguanide type cleaning/disinfection system as it just isn't as effective at destroying more persistent microbiological agents. I use a two part peroxide for that reason.

I also find that the biguanide system I was recommended to use for RGP lenses seems to create grit from dried solution products, which is very uncomfortable in my eyes.

knotlob
Could that be the reason that peroxide is widely used as a disinfectant but I've never heard of biguinide?
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  #24 (permalink)  
Old 07-29-2010, 09:51 AM
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Default

Quote:
Originally Posted by VirginiaEyeDr View Post
. . . "Biguanides" . . . [tend] to bind proteins in your tears to high silicon/water content Contact lenses
That sounds like the opposite of cleaning to me. Seems like the effect of biguanides is to make sure the proteins never come off.
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  #25 (permalink)  
Old 07-29-2010, 09:58 AM
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Default

Quote:
Originally Posted by Nichobec View Post
Could that be the reason that peroxide is widely used as a disinfectant but I've never heard of biguinide?
Biguinides are widely used in Multi Purpose Cleaning Disinfecting solutions.

knotlob
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  #26 (permalink)  
Old 07-29-2010, 10:57 AM
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Default

Quote:
Originally Posted by Knotlob View Post
Biguinides are widely used in Multi Purpose Cleaning Disinfecting solutions.

knotlob
So, based on what yournamehere copied and pasted, these multi-purpose cleaning solutions which contain biguinides are not intended to clean high silicon/water content contact lenses because VirginiaEyeDr says they bind to the proteins in the tear layer.

Something like that?
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  #27 (permalink)  
Old 07-29-2010, 11:23 AM
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Default Biofinity

Quote:
Originally Posted by Guinness View Post
So, based on what yournamehere copied and pasted, these multi-purpose cleaning solutions which contain biguinides are not intended to clean high silicon/water content contact lenses because VirginiaEyeDr says they bind to the proteins in the tear layer.

Something like that?
They are more likly to bind proteins to the lens surface on SiHi lenses,but not on all patients.
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  #28 (permalink)  
Old 07-29-2010, 11:37 AM
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Default Are Biofinity Contact Lenses SiHi?

Quote:
Originally Posted by VirginiaEyeDr View Post
They are more likely to bind proteins to the lens surface on SiHi lenses,but not on all patients.
So what about Biofinity lenses. Are they SiHi? Do you pronounce that "sigh high"?
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  #29 (permalink)  
Old 07-29-2010, 12:47 PM
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Default

Quote:
Originally Posted by Kyleden View Post
So what about Biofinity lenses. Are they SiHi? Do you pronounce that "sigh high"?
Biofinity are silicone hydrogel lenses.

I understand that silicone hydrogel (SiH) lenses are less prone to protein deposits than conventional hydrogel lenses. I prefer hydroxide cleaning systems, but realise Multi Purpose Cleaning Disinfection systems are probably more convenient to the average contact lens wearer.

But as VirginiaEyeDr says, it will depend to some extent on the individual's tear chemistry.

knotlob
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  #30 (permalink)  
Old 07-30-2010, 10:59 AM
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Default

Quote:
Originally Posted by Kyleden View Post
So what about Biofinity lenses. Are they SiHi? Do you pronounce that "sigh high"?
Did somebody say "sci-fi"?
Attached Images
File Type: jpg image006.jpg (65.2 KB, 76 views)
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  #31 (permalink)  
Old 08-03-2010, 11:59 AM
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Default sIhI

Quote:
Originally Posted by Kyleden View Post
So what about Biofinity lenses. Are they SiHi? Do you pronounce that "sigh high"?
Yes,Silicone Hydrogel 52%,water 48%
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  #32 (permalink)  
Old 08-03-2010, 03:34 PM
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Default

Quote:
Originally Posted by UNIT View Post
Did somebody say "sci-fi"?
Um, no, UNIT, That's SiHi. Sorry.
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  #33 (permalink)  
Old 08-05-2010, 11:25 AM
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Default

Quote:
Originally Posted by Knotlob View Post
I have to take VirginaEyeDoctor's word for the time being. However, I accept his/her statement as I think I have seen words to that effect elsewhere, but would prefer to see the academic backup.

I don't really like to use a Biguanide type cleaning/disinfection system as it just isn't as effective at destroying more persistent microbiological agents. I use a two part peroxide for that reason.

knotlob
So how common are these "more persistent microbial agents"? Are they something that your average Biofinity wearers need to be concerned about?
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  #34 (permalink)  
Old 08-05-2010, 11:30 AM
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Quote:
Originally Posted by KITT View Post
So how common are these "more persistent microbial agents"? Are they something that your average Biofinity wearers need to be concerned about?
I was thinking of your everyday Acanthamoeba kerititis bacteria, which is present everywhere, especially in tap water, swimming pools, brackish water, etc. Rare to get infected but very unpleasant and sight threatening if it contaminates your contact lenses/cornea. Biguinides are not proven to kill these. A two step peroxide disinfection system is effective against the bacteria.

knotlob
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  #35 (permalink)  
Old 08-05-2010, 01:26 PM
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Default Your Recommendation

Quote:
Originally Posted by Knotlob View Post
I was thinking of your everyday Acanthamoeba kerititis bacteria, which is present everywhere, especially in tap water, swimming pools, brackish water, etc. Rare to get infected but very unpleasant and sight threatening if it contaminates your contact lenses/cornea. Biguinides are not proven to kill these. A two step peroxide disinfection system is effective against the bacteria.

knotlob
That's good to know, Knotlob. Would you recommend the disinfecting two-step for all contact lenses besides the one you just wear once?
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  #36 (permalink)  
Old 08-05-2010, 02:26 PM
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Quote:
Originally Posted by madeinshades View Post
That's good to know, Knotlob. Would you recommend the disinfecting two-step for all contact lenses besides the one you just wear once?
I used to wear yearly lenses and then switched to Biofinity. I always used the peroxide system for cleaning/disinfection. In Europe I always used the 2 step system, but I think in N America/Canada it is only a single step peroxide system, which is available and I used that when in Canada.

I now wear RGP lenses and didn't like the Multi Purpose Solution I was recommended to use, so eventually got the manufacturer's agreement to use a two step peroxide system for these too. That worked fine for cleaning. However, after a few days, the RGP lenses become a bit uncomfortable and so I had to use a RGP soaking/wetting solution after the peroxide. I subsequently switched to another Multi Purpose Cleaning Solution but will search for others to try as well.

So, in summary, peroxide very good for soft lenses, not very good/comfortable without a soaking solution for RGP lenses.

knotlob
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  #37 (permalink)  
Old 08-05-2010, 03:08 PM
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Default That's a Good Question

Quote:
Originally Posted by Knotlob View Post
I used to wear yearly lenses and then switched to Biofinity. I always used the peroxide system for cleaning/disinfection. In Europe I always used the 2 step system, but I think in N America/Canada it is only a single step peroxide system, which is available and I used that when in Canada.

I now wear RGP lenses and didn't like the Multi Purpose Solution I was recommended to use, so eventually got the manufacturer's agreement to use a two step peroxide system for these too. That worked fine for cleaning. However, after a few days, the RGP lenses become a bit uncomfortable and so I had to use a RGP soaking/wetting solution after the peroxide. I subsequently switched to another Multi Purpose Cleaning Solution but will search for others to try as well.

So, in summary, peroxide very good for soft lenses, not very good/comfortable without a soaking solution for RGP lenses.

knotlob
Thanks for the information, knotlob, and thanks to madeinshades for the question.
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  #38 (permalink)  
Old 08-16-2010, 03:01 PM
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Default

Quote:
Originally Posted by VirginiaEyeDr View Post
Aviod solutions containing "Biguanides" as the disinfecting agent. This compound tends to bind proteins in your tears to high silicon/water content Contact lenses
If biguanides are bad for contact lenses, why do they put them in cleaning solutions?
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  #39 (permalink)  
Old 08-16-2010, 03:08 PM
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Default

Quote:
Originally Posted by Guinness View Post
If biguanides are bad for contact lenses, why do they put them in cleaning solutions?
My guess would be cost.
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  #40 (permalink)  
Old 08-16-2010, 03:13 PM
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Quote:
Originally Posted by Caligula View Post
My guess would be cost.
Probably convenience also. You don't need to wait for the disinfecting solution to be neutralised like peroxides. You can put the Multi Purpose Cleaning/Disinfecting Solution directly into your eye.

knotlob
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  #41 (permalink)  
Old 08-16-2010, 03:26 PM
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Default Silicon and Water

Quote:
Originally Posted by VirginiaEyeDr View Post
Aviod solutions containing "Biguanides" as the disinfecting agent. This compound tends to bind proteins in your tears to high silicon/water content Contact lenses
So which contact lenses have this "high silicon/water content"? Would they all be a certain type, like monthly disposable? What about Biofinity?
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  #42 (permalink)  
Old 08-17-2010, 10:39 AM
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Default

Quote:
Originally Posted by Caligula View Post
My guess would be cost.
They are not bad for contats, but bad for germs. Think of them as a preservative, some people react most don't.
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  #43 (permalink)  
Old 08-17-2010, 11:50 AM
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Default

Quote:
Originally Posted by Kyleden View Post
So which contact lenses have this "high silicon/water content"? Would they all be a certain type, like monthly disposable? What about Biofinity?
Biofinity contact lenses are composed of 52% comfilcon A and 48% water. That's almost a 50/50 split.
Anyway, how can something be both high silicone and high water content? Isn't that what you mean, VirginiaEyeDr, when you said "[Biguanide] tends to bind proteins in your tears to high silicon/water content contact lenses"?
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  #44 (permalink)  
Old 08-22-2010, 10:18 PM
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Default

There is nothing wrong with Dymed type solutions when using HEMA lenses, although I've always recommended peroxide. However, each material is different. The only solutions specifically recommended for use with silicone gel lenses are 1) Alcon Replenish, 2) AMO Complete and 3) peroxide systems.
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  #45 (permalink)  
Old 08-23-2010, 10:25 AM
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Default

Quote:
Originally Posted by Contact Lens Fitter View Post
There is nothing wrong with Dymed type solutions when using HEMA lenses, although I've always recommended peroxide. However, each material is different. The only solutions specifically recommended for use with silicone gel lenses are 1) Alcon Replenish, 2) AMO Complete and 3) peroxide systems.
What are "Dymed type solutions"?
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  #46 (permalink)  
Old 08-23-2010, 11:07 AM
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Default

see the top few messages
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  #47 (permalink)  
Old 08-23-2010, 11:50 AM
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Quote:
Originally Posted by Contact Lens Fitter View Post
see the top few messages
From post #18: "The 'biguanide' I refer to is polyaminopropyl biguanide (DYMED) and is used in Multi Purpose Disinfecting & Cleaning Solutions." So it's an ingredient in contact lens multi-purpose solution.
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  #48 (permalink)  
Old 08-23-2010, 04:57 PM
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Default Thanks

Quote:
Originally Posted by Juicer View Post
From post #18: "The 'biguanide' I refer to is polyaminopropyl biguanide (DYMED) and is used in Multi Purpose Disinfecting & Cleaning Solutions." So it's an ingredient in contact lens multi-purpose solution.
Thanks for pulling it all together, Juicer.
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  #49 (permalink)  
Old 11-11-2010, 05:40 PM
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Default You Heard Me

Quote:
Originally Posted by UNIT View Post
Did somebody say "sci-fi"?
That's cute, UNIT. Nice picture, too.
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  #50 (permalink)  
Old 12-10-2010, 12:24 PM
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Default I Didn't Know That

Quote:
Originally Posted by Knotlob View Post
Biguinides are widely used in Multi Purpose Cleaning Disinfecting solutions.

knotlob
Oh . . . I guess I'm just out of touch.
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